--- title: "On Folding Proteins" date: 2020-12-23 description: "On Folding Proteins" --- Merry Christmas, everyone. [What is the “protein folding problem”? A brief explanation](https://rootsofprogress.org/alphafold-protein-folding-explainer) > Today Google DeepMind announced that their deep learning system AlphaFold has achieved unprecedented levels of accuracy on the “protein folding problem”, a grand challenge problem in computational biochemistry. > > What is this problem, and why is it hard? A good primer on protein folding, the challenges involved, and, of course, recent developments.